Single port illumination systems result in substantial shadowed regions obscuring vision when illuminating complex topography such as, for example, human anatomical structures or other biological materials. Existing illumination projection in imaging systems may feature anamorphic projection to match the imaging field of view, but typically only feature a single illumination port and are not configured for close working distances. Matching the illumination profile to the imaging field of view is one method of conserving illumination power, while multiple illumination ports may be used to provide even illumination across the field of view. In many applications of imaging systems, such as in medical imaging and especially in fluorescence medical imaging, it may be challenging to achieve even, full field illumination of the imaging field of view, and also to provide a sufficient intensity of illumination to yield a sufficiently strong imaging signal. Illumination is an important component of imaging systems such as, for example, broadband imaging systems with self-contained illumination. More specifically, the disclosure relates to illumination and imaging of a target material. The present disclosure relates generally to medical illumination and imaging. 10, 2017, the entire contents of each of which are hereby incorporated by reference herein. This application is a continuation of U.S.
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